Triazole macrocycle systems

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United States of America Patent

PATENT NO 9493509
SERIAL NO

14677679

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Abstract

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The present invention provides novel peptidomimetic macrocycles and methods for their preparation and use, as well as amino acid analogs and macrocycle-forming linkers, and kits useful in their production. Macrocycles of the invention include triazole moieties that crosslink amino acid side chains. The cross links can stabilize a secondary structure of a peptidomimetic macrocycle, such as an α-helix.

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Patent Owner(s)

Patent OwnerAddress
AILERON THERAPEUTICS INC281 ALBANY STREET CAMBRIDGE MA 02139

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Nash, Huw M Concord, US 72 2496

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