Method of neonatal serological diagnosis

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United States of America Patent

PATENT NO 9493811
APP PUB NO 20140178916A1
SERIAL NO

14238107

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Abstract

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The present invention provides a method for determining the amino acid polymorphisms of heavy gamma chain of immunoglobulins G by a proteomic approach. This method distinguishes the immunoglobulins of the mother and those of the newborn in a blood sample obtained during the first months of the child's life. The invention also relates to the use of this method in the early diagnosis of vertically transmitted diseases in the neonate. The invention also provides peptides distinctive of G3m and IGHG3 alleles, and a kit comprising said peptides.

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Patent Owner(s)

Patent OwnerAddress
UNIVERSITÉ PARIS CITÉ85 BOULEVARD SAINT-GERMAIN PARIS 75006

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Dechavanne, Celia Paris, FR 1 0
Dugoujon, Jean-Michel Leguevin, FR 1 0
Guillonneau, Francois Droue/Drouette, FR 1 0
Lefranc, Marie-Paule Clapiers, FR 2 8
Migot-Nabias, Florence Eaubonne, FR 1 0

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