Tools for the identification of Lingo-1, Lingo-2, Lingo-3 and Lingo-4 ligands, and uses thereof

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United States of America Patent

PATENT NO 9494585
APP PUB NO 20130090249A1
SERIAL NO

13637952

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Abstract

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The present invention relates to a system comprising coupling products formed by a monomer of a protein chosen from Lingo-1, Lingo-2, Lingo-3 and Lingo-4 and by a probe emitting a signal when said monomer undergoes conformational changes, and to a screening method using said system, enabling ligands of a protein chosen from Lingo-1, Lingo-2, Lingo-3 and Lingo-4 to be identified. The present invention is industrially applicable in the field of methods for detecting molecules, for detecting interaction between molecules and for molecular screening, and also in the medical field.

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Patent Owner(s)

Patent OwnerAddress
CENTRE NATIONAL DE LA RECHERCHE SCENTIFIQUE-CNRS-3 RUE MICHEL-ANGE PARIS CEDEX 16 75794

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Benedetti, Helene Saint-Jean-de-Braye, FR 1 0
Morisset-Lopez, Severine Saint-Pryve-Saint-Mesmin, FR 1 0

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