Flaviviruses expressing the prM, E, and NS1 proteins of other flaviviruses and uses thereof

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United States of America Patent

PATENT NO 9499588
APP PUB NO 20110311579A1
SERIAL NO

13136081

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Abstract

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This invention provides flavivirus vaccines that comprise live-attenuated flaviviruses and methods of making and using these vaccines. The flavivirus vaccines described herein possess higher potency due to in situ production of additional immunogens in a way that mimics viral infection and the vaccines have potential for higher potency, reducing costs for production and delivery.

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Patent Owner(s)

  • BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Ishikawa, Tomohiro Kobe, JP 66 1046
Mason, Peter W Somerville, US 11 130

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