Stabilizing composition for biological materials

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United States of America Patent

PATENT NO 9504750
SERIAL NO

13849941

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Abstract

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Dry stabilizing compositions for bioactive materials include sugars and hydrolyzed proteins, and may be formed into tablets or other forms providing enhanced stability for the bioactive material. Compositions containing the bioactive materials may be produced by a method that includes (a) combining the bioactive material with other ingredients in an aqueous solvent to form a viscous slurry; (b) snap-freezing the slurry in liquid nitrogen to form solid frozen particles, beads, droplets or strings; (c) primary drying by water removal under vacuum of the product of step (b) while maintaining it at a temperature above its freezing temperature; and (d) secondary drying of the product of step (c) at maximum vacuum and a temperature of 20° C. or higher for a time sufficient to reduce the water activity to below 0.3 Aw.

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Patent Owner(s)

Patent OwnerAddress
ADVANCED BIONUTRITION CORP7155 COLUMBIA GATEWAY DRIVE SUITE H COLUMBIA MD 21046

International Classification(s)

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Carpenter, Brian Baltimore, US 25 116
Drewes, Roger Hockessin, US 7 71
Harel, Moti Pikesville, US 30 315
Jennings, Kimberly Laurel, US 3 15
Raditsis, Elizabeth Columbia, US 3 15
Rice, Trisha Columbia, US 5 17
Scarbrough, January Silver Spring, US 5 43
Tang, Qiong Columbia, US 13 38

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