Graphitic nanotubes in luminescence assays

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United States of America Patent

PATENT NO 9505619
APP PUB NO 20060160246A1
SERIAL NO

11385277

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Abstract

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Graphitic nanotubes, which include tubular fullerenes (commonly called “buckytubes”) and fibrils, which are functionalized by chemical substitution, are used as solid supports in electrogenerated chemiluminescence assays. The graphitic nanotubes are chemically modified with functional group biomolecules prior to use in an assay. Association of electrochemiluminescent ruthenium complexes with the functional group biomolecule-modified nanotubes permits detection of molecules including nucleic acids, antigens, enzymes, and enzyme substrates by multiple formats.

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Patent Owner(s)

  • IGEN, INC.;MESO SCALE TECHNOLOGIES, LLC.

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Dong, Liwen Rockville, US 55 554
Fischer, Alan Cambridge, US 47 2406
Hoch, Robert Hensonville, US 68 2160
Jameison, Fabian Gaithersburg, US 7 425
Leland, Jonathan K Silver Spring, US 52 2119
Liang, Pam Rockville, US 12 485
Lu, Ming Lanham, US 151 1919
Martin, Mark T Bethesda, US 44 863
Massey, Richard J Rockville, US 48 1217

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