Phosphorylated A2A receptor agonists

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United States of America Patent

PATENT NO 9505796
APP PUB NO 20140288019A1
SERIAL NO

14108010

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Abstract

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A phosphorylated A2A receptor agonist providing agonist properties on the A2A receptor after dephosphorylation the phosphorylated A2A receptor agonist comprises a ribosyl moiety and a purine moiety and being phosphorylated at the 5′-position of the ribose moiety except adenosine monophosphate (AMP), adenosine diphosphate (ADP) or adenosine triphosphate (ATP), a medicament containing the compound of the invention including ADP and the use of the compound of the invention including ATP and ADP for several medical indications e.g. inflammatory events. In particular, compounds of formula (I) are also disclosed.

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Patent Owner(s)

Patent OwnerAddress
CROZET MEDICAL GMBHMELIESALLEE 13 DUSSELDORF 40597

International Classification(s)

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
El-Tayeb, Ali Bonn, DE 7 7
Iqbal, Jamshed Bonn, DE 4 7
Muller, Christa Bonn, DE 7 10
Schrader, Jurgen Dusseldorf, DE 32 337

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