Albumin-insulin fusion proteins

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United States of America Patent

PATENT NO 9505823
APP PUB NO 20080057004A1
SERIAL NO

11835114

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Abstract

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Disclosed are fusion proteins that include albumin fused to a polypeptide that has insulin activity. The fusion proteins may include albumin fused to insulin or an insulin analog. In particular, the fusions proteins may include albumin fused to a single chain insulin analog. The fusion proteins may exhibit extended insulin activity in vivo or in vitro relative to insulin that is not fused to albumin. The fusion proteins may be formulated as aerosol compositions.

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Patent Owner(s)

Patent OwnerAddress
TEVA BIOPHARMACEUTICALS USA INC9410 KEY WEST AVENUE ROCKVILLE MD 20850

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Bell, Adam C Germantown, US 3 17
Rosen, Craig A Laytonsville, US 736 11451
Sanyal, Indrajit Bethesda, US 9 81
Zhao, Qinghai Gaithersburg, US 6 22

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