Antibody constructs for influenza M2 and CD3
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United States of America Patent
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Nov 29, 2016
Grant Date -
Feb 11, 2016
app pub date -
Mar 17, 2014
filing date -
Mar 15, 2013
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Abstract
The present invention relates to an antibody construct comprising a first human binding domain specific for the extracellular part of the influenza envelope protein M2 (M2e) and a second domain specific for CD3. Moreover, the invention provides a nucleic acid molecule encoding the antibody construct, a vector comprising said nucleic acid molecule and a host cell transformed or transfected with said nucleic acid molecule or vector. Furthermore, the invention provides a process for the production of the antibody construct of the invention, a pharmaceutical composition comprising said antibody construct, a medical use/method of treatment relating to said antibody construct, and a kit comprising said antibody construct.
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