Soluble needle arrays for delivery of influenza vaccines

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United States of America Patent

PATENT NO 9517205
SERIAL NO

13817814

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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Influenza vaccines are administered using solid biodegradable microneedles. The microneedles are fabricated from the influenza vaccine in combination with solid excipient(s) and, after penetrating the skin, they dissolve in situ and release the vaccine to the immune system. The influenza vaccine is (i) a purified influenza virus surface antigen vaccine, rather than a live vaccine or a whole-virus or split inactivated vaccine (ii) an influenza vaccine prepared from viruses grown in cell culture, not eggs, (iii) a monovalent influenza vaccine e.g. for immunizing against a pandemic strain, (iv) a bivalent vaccine, (v) a tetravalent or >4-valent vaccine, (vi) a mercury-free vaccine, or (vii) a gelatin-free vaccine.

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Patent Owner(s)

  • SEQIRUS UK LIMITED;THERAJECT, INC.

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Kwon, Sung-Yun Cambridge, US 20 902
O'Hagan, Derek Cambridge, US 140 2505
Singh, Manmohan Cambridge, US 103 2287

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