Induction of mucosal tolerance to antigens

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United States of America Patent

PATENT NO 9526750
SERIAL NO

14216842

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Abstract

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The present invention relates to the induction of tolerance to antigens, by mucosal, preferably oral delivery of the antigen in combination with an immunomodulating compound producing micro-organism. More specifically, the invention relates to the induction of Foxp3+ and/or IL-10 and/or TGF-β producing regulatory T-cells, capable of suppressing undesired immune responses toward an antigen, by oral delivery of said antigen in combination with an immunosuppressing cytokine secreting micro-organism.

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Patent Owner(s)

Patent OwnerAddress
INTREXON ACTOBIOTICS NVZWIJNAARDE

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Rottiers, Pieter De Pinte, BE 21 128
Snoeck, Veerle Zingem, BE 30 121

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