Methods for the induction of ebola virus-specific immune responses comprising administering a replication-defective chimpanzee adenovirus vector expressing the ebola virus glycoprotein

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United States of America Patent

PATENT NO 9526777
APP PUB NO 20130101618A1
SERIAL NO

13641655

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Abstract

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This invention provides vaccines for inducing an immune response and protection against filovirus infection for use as a preventative vaccine in humans. In particular, the invention provides chimpanzee adenoviral vectors expressing filovirus proteins from different strains of Ebola virus (EBOV) or Marburg virus (MARV).

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Patent Owner(s)

  • SMITHKLINE BEECHAM BIOLOGICALS S.A.;THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Ammendola, Virginia Naples, IT 21 56
Asiedu, Clement Olney, US 5 30
Cheng, Cheng Rockville, US 74 174
Colloca, Stefano Rome, IT 40 156
Cortese, Riccardo Rome, IT 38 138
Nabel, Gary J Washington, US 124 3473
Nicosia, Alfredo Rome, IT 50 197
Sullivan, Nancy J Kensington, US 12 38

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