Steroid analogues for neuroprotection

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United States of America Patent

PATENT NO 9527881
APP PUB NO 20110263553A1
SERIAL NO

12918036

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Abstract

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Provided are steroid analogues functionalized with polar substituents at the C3 and/or C20 positions of the steroid ring system that exhibit improved water solubility. Also provided are pharmaceutical compositions comprising the steroid analogues and methods using the novel steroid analogues for the treatment and prevention of neurodegeneration in a patient following injury to the central nervous system.

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Patent Owner(s)

Patent OwnerAddress
EMORY UNIVERSITY1599 CLIFTON ROAD 4TH FLOOR ATLANTA GA 30322

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Guthrie, David B Atlanta, US 14 83
Liotta, Dennis C Atlanta, US 138 2372
Lockwood, Mark A John's Creek, US 12 69
Macnevin, Christopher Durham, US 3 13
Natchus, Michael G Alpharetta, US 31 102
Sayeed, Iqbal Atlanta, US 18 145
Stein, Donald G Atlanta, US 24 371

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