In vitro sorting method

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United States of America Patent

PATENT NO 9528106
SERIAL NO

13733473

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Abstract

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The invention describes a method for isolating one or more genetic elements encoding a gene product having a desired activity, comprising of the steps of: (a) compartmentalizing genetic elements into microcapsules; (b) expressing the genetic elements to produce their respective gene products within the microcapsules; (c) sorting the genetic elements which produce the gene product having a desired activity. The invention enables the in vitro evolution of nucleic acids by repeated mutagenesis and iterative applications of the method of the invention.

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Patent Owner(s)

  • MEDICAL RESEARCH COUNCIL

International Classification(s)

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Griffiths, Andrew Cambridge, GB 39 4325
Tawfik, Dan Cambridge, GB 16 2288

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