Methods and means for efficient skipping of exon 45 in duchenne muscular dystrophy pre-mRNA

Number of patents in Portfolio can not be more than 2000

United States of America Patent

PATENT NO 9528109
APP PUB NO 20150073037A1
SERIAL NO

14542183

Stats

ATTORNEY / AGENT: (SPONSORED)

Importance

Loading Importance Indicators... loading....

Abstract

See full text

The invention relates to a method for inducing or promoting skipping of exon 45 of DMD pre-mRNA in a Duchenne Muscular Dystrophy patient, preferably in an isolated (muscle) cell, the method comprising providing an isolated muscle cell with a molecule that binds to a continuous stretch of at least 21 nucleotides within the exon. The invention further relates to such molecule used in the method.

Loading the Abstract Image... loading....

First Claim

See full text

Family

Loading Family data... loading....

Patent Owner(s)

Patent OwnerAddress
ACADEMISCH ZIEKENHUIS LEIDENALBINUSDREEF 2 LEIDEN NO-2333 ZA
BIOMARIN TECHNOLOGIES B V2333 CH LEIDEN

International Classification(s)

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
De, Kimpe Josephus Johannes Utrecht, NL 35 1153
Platenburg, Gerard Johannes Voorschoten, NL 37 1254
Rus, Adriana Marie Hoofddorp, NL 10 160
Van, Deutekom Judith Christina Theodora Dordrecht, NL 64 2331
Van, Ommen Garrit-Jan Boudewijn Amsterdam, NL 43 1951

Cited Art Landscape

Load Citation

Patent Citation Ranking

Forward Cite Landscape

Load Citation

Maintenance Fees

Fee Large entity fee small entity fee micro entity fee due date
11.5 Year Payment $7400.00 $3700.00 $1850.00 Jun 27, 2028
Fee Large entity fee small entity fee micro entity fee
Surcharge - 11.5 year - Late payment within 6 months $160.00 $80.00 $40.00
Surcharge after expiration - Late payment is unavoidable $700.00 $350.00 $175.00
Surcharge after expiration - Late payment is unintentional $1,640.00 $820.00 $410.00