Rare clonotypes and uses thereof

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United States of America Patent

PATENT NO 9528160
APP PUB NO 20130196328A1
SERIAL NO

13834794

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Abstract

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The invention is directed to a method of selecting disease-correlated clonotypes that have a reduced likelihood of producing a false positive signal of relapse when, used to monitor minimal residual disease. In accordance with the invention, candidate correlating clonotype are obtained from a patient, the rarity of each is determined either by comparison with a clonotype database or a clonotype model, and one or more of the rarest of such clonotypes are used to monitor the minimal residual disease.

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Patent Owner(s)

  • ADAPTIVE BIOTECHNOLOGIES CORP.

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Faham, Malek Pacifica, US 97 5030
Moorhead, Martin San Mateo, US 16 1076
Pepin, Francois San Bruno, US 13 257

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