Medium-chain length fatty acids and glycerides as nephroprotection agents
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United States of America Patent
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Jan 3, 2017
Grant Date -
Nov 11, 2010
app pub date -
Nov 3, 2008
filing date -
Nov 2, 2007
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Abstract
Use of medium-chain length fatty acids such as capric acid, caprylic acid or lauric acid and their salts or mono- or di- or triglycerides as nephroprotection agents to protect against renal failure progression in chronic kidney diseases This includes the treatment of kidney diseases associated with nephrectomy, renal fibrosis, glomerular sclerosis and end-stage renal disease Also includes the protection of the kidney against cytotoxic agent used in chemotherapy or autoimmune diseases or transplantation Further includes the treatment of renal failure progression associated with hypertension, infarct, tumor, diabetes mellitus, autoimmunity or inflammation.
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