Morpholinos, morpholino upregulating, and associated methods

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United States of America Patent

PATENT NO 9534222
SERIAL NO

14358572

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Abstract

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Various methods and compositions relating to vascular endothelial growth factor receptor 2 (VEGFR2) are provided. In one aspect, a method of increasing expression of the soluble form of VEGFR2 (sVEGFR2) in a subject can include binding an antisense morphoiino to an exon13-intron13 splicing site of VEGFR2 mRNA such that the VEGFR2 niRNA is spliced into a sVEGFR2 isoform.

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Patent Owner(s)

  • UNIVERSITY OF UTAH

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Ambati, Balamurali K Sandy, US 23 138
Uehara, Hironori Salt Lake City, US 8 17

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