Method for monofluoromethylation of organic substrates to prepare biologically active organic compounds

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United States of America Patent

PATENT NO 9540413
APP PUB NO 20130225844A1
SERIAL NO

13701207

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Abstract

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Described herein is a process for the preparation of monofluoromethylated organic biologically active compounds using monofluoromethylated reagents. Fluticasone Propionate and Fluticasone Furoate can be prepared using, for example, S-monofluoromethyl-S-phenyl-2,3,4,5-tetramethylphenylsulfonium tetrafluoroborate as monofluoromethylating reagent instead of bromofluoromethane.

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Patent Owner(s)

Patent OwnerAddress
HOVIONE INTER LIMITED6000 LUCERNE 7

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Leitao, Emilia Perpetua Tavares Sao Marcos, PT 7 5

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