Treatment of allergic diseases with recombinant antibodies

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United States of America Patent

PATENT NO 9546219
SERIAL NO

14374679

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Abstract

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Recombinant antibodies (including binding fragments thereof) that bind IgE are described, along with compositions and methods of using the same in the treatment of subjects in need thereof, including subjects afflicted with atopic dermatitis, allergic rhinitis, allergic conjunctivitis, urticaria, gastro-intestinal inflammation, or oral-pharyngeal inflammation. In some embodiments, the antibody is a single chain variable fragment (scFv) or a disulfide linked variable fragment (sdFv). In some embodiments, the subject is a dog, cat, or horse.

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Patent Owner(s)

  • NORTH CAROLINA STATE UNIVERSITY

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Hammerberg, Bruce Raleigh, US 7 12

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