Cyclodextrin-based polymers for therapeutics delivery
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United States of America Patent
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Jan 24, 2017
Issued Date -
N/A
app pub date -
Oct 24, 2013
filing date -
Sep 6, 2002
priority date (Note) -
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status (Latency Note)
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Abstract
The present invention relates to novel compositions of therapeutic cyclodextrin containing polymeric compounds designed as a carrier for small molecule therapeutics delivery and pharmaceutical compositions thereof. These cyclodextrin-containing polymers improve drug stability and solubility, and reduce toxicity of the small molecule therapeutic when used in vivo. Furthermore, by selecting from a variety of linker groups and targeting ligands the polymers present methods for controlled delivery of the therapeutic agents. The invention also relates to methods of treating subjects with the therapeutic compositions described herein. The invention further relates to methods for conducting pharmaceutical business comprising manufacturing, licensing, or distributing kits containing or relating to the polymeric compounds described herein.
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International Classification(s)
- A61K:PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOS....
- C08G:MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN B....
- B82Y:SPECIFIC USES OR APPLICATIONS OF NANO-STRUCTURES; ....
- C08F:MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONL....
- G06Q:DATA PROCESSING SYSTEMS OR METHODS, SPECIALLY ADAP....
- C08B:POLYSACCHARIDES; DERIVATIVES THEREOF
- G06F:ELECTRIC DIGITAL DATA PROCESSING
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