Therapeutic uses of modified relaxin polypeptides

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United States of America Patent

PATENT NO 9567386
SERIAL NO

13774349

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Abstract

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Modified relaxin polypeptides and their uses, including therapeutic uses thereof for the treatment of a fibrotic disorder or heart failure are provided. Exemplary embodiments provide for the use of relaxin polypeptides which include one or more amino acid substitutions with natural or non-naturally encoded amino acids, and/or linkage to a water-soluble polymer, such as polyethylene glycol.

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Patent Owner(s)

Patent OwnerAddress
AMBRX INC10975 NORTH TORREY PINES ROAD LA JOLLA CA 92037

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
de, Dios Kristine San Diego, US 11 184
Hewet, Amha Chula Vista, US 15 140
Knudsen, Nick Escondito, US 47 1108
Kraynov, Vadim San Diego, US 43 902
Pinkstaff, Jason Encinitas, US 32 740
Sullivan, Lorraine San Diego, US 12 210

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