Devices and methods for modulation of bone erosion

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United States of America Patent

PATENT NO 9572983
SERIAL NO

13851013

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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Devices and methods for stimulation of the vagus nerve to modulate (e.g., reduce, suppress, etc.) bone erosion. Methods and apparatus for modulating bone erosion may modulate levels of Receptor Activator for Nuclear Factor κ B Ligand (RANKL), and/or to modulate (increase, enhance, etc.) osteoprotegerin (OPG) and/or OPG/RANKL ratio. Devices may include electrical stimulation devices that may be implanted, and may be activated to apply current for a proscribed duration, followed by a period without stimulation.

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Patent Owner(s)

  • SETPOINT MEDICAL CORPORATION

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Faltys, Michael A Valencia, US 97 7283
Levine, Jacob A Queens, US 28 882
Zitnik, Ralph J Santa Barbara, US 10 333

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