Devices and methods for modulation of bone erosion

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United States of America Patent

PATENT NO 9572983
SERIAL NO

13851013

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Abstract

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Devices and methods for stimulation of the vagus nerve to modulate (e.g., reduce, suppress, etc.) bone erosion. Methods and apparatus for modulating bone erosion may modulate levels of Receptor Activator for Nuclear Factor κ B Ligand (RANKL), and/or to modulate (increase, enhance, etc.) osteoprotegerin (OPG) and/or OPG/RANKL ratio. Devices may include electrical stimulation devices that may be implanted, and may be activated to apply current for a proscribed duration, followed by a period without stimulation.

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Patent Owner(s)

Patent OwnerAddress
SETPOINT MEDICAL CORPORATION25101 RYE CANYON LOOP VALENCIA CA 91355

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Faltys, Michael A Valencia, US 102 7814
Levine, Jacob A Queens, US 34 1092
Zitnik, Ralph J Santa Barbara, US 12 414

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