N-heterocyclic carbene gold complexes with anticancer properties and methods of use thereof

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United States of America Patent

PATENT NO 9573967
APP PUB NO 20160326187A1
SERIAL NO

14705627

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Abstract

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Monomeric gold(I) complexes as anticancer agents. The gold(I) complexes are coordinated to mixed ligands: one N-heterocyclic carbene ligand and one monodentate dithiocarbamate-based ligand. Pharmaceutical compositions incorporating the gold(I) complexes, methods of synthesis, methods of treating cancer and methods of inhibiting cancer cell proliferation and inducing cancer cell apoptosis are also provided.

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Patent Owner(s)

Patent OwnerAddress
KING FAHD UNIVERSITY OF PETROLEUM AND MINERALSDHAHRAN

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Altaf, Muhammad Dhahran, SA 44 54
Isab, Anvarhusein Abdulkadir Dhahran, SA 23 35

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