Multi-leu peptides and analogues thereof as selective PACE4 inhibitors and effective antiproliferative agents

Number of patents in Portfolio can not be more than 2000

United States of America Patent

PATENT NO 9573974
APP PUB NO 20140256646A1
SERIAL NO

14149857

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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Disclosed herein are PACE4 inhibitors, compositions comprising PACE4 inhibitors and their uses thereof for lowering PACE4 activity, reducing cell proliferation, reducing tumor growth, reducing metastasis formation, preventing and/or treating cancer. Also provided are methods for lowering PACE4 activity, reducing the proliferation of a cell, reducing tumor growth and/or treating and preventing cancer. Methods for screening PACE4 inhibitors and cell proliferation inhibitors are further provided.

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Patent Owner(s)

  • SOCPRA SCIENCES ET GENIE S.E.C.;LA SOCIETE DE COMMERCIALISATION DES PRODUITS DE LA RECHERCHE APPLIQUEE SOCPRA - SCIENCES SANTE ET HUMAINES S.E.C.

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Day, Robert Sherbrooke, CA 35 684
Fugére, Martin San Diego, US 1 0
Neugebauer, Witold A Ottawa, CA 8 15

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