Methods and apparatus for independent control of product and reactant concentrations

Number of patents in Portfolio can not be more than 2000

United States of America Patent

PATENT NO 9574167
APP PUB NO 20140234954A1
SERIAL NO

14180403

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Abstract

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A microreactor with a reaction chamber comprising two sub-chambers with reconfigurable volumes, an input conduit with input valve, an un-filtered output conduit with first output valve, and a filtered output conduit with a second output valve is used to perform a method to control a different dilution rate for cells and molecules in continuous culture bioprocesses. In preferred embodiments flow control is achieved using the difference in volume of the two sub-chambers.

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Patent Owner(s)

Patent OwnerAddress
EMD MILLIPORE CORPORATION400 SUMMIT DRIVE BURLINGTON MA 01803

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Lee, Harry Malden, US 33 1095
Lee, Kevin Shao-Kwan Cambridge, US 10 64

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