Methods and reagents for efficient and targeted delivery of therapeutic molecules to CXCR4 cells

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United States of America Patent

PATENT NO 9580468
SERIAL NO

13979560

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Abstract

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Conjugates comprising a targeting moiety specific for the CXCR4 and based on the polyphemusin-derived peptide and a therapeutic or imaging agent are provided. Therapeutic and diagnostic methods with the conjugates which require specific targeting to CXCR4+ cells are provided as well.

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Patent Owner(s)

Patent OwnerAddress
INSTITUT RECERCA HOSPITAL DE LA SANTA CREU I SANT PAUC/SANT ANTONI MARIA CLARET 167 BARCELONA 08025

International Classification(s)

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Céspedes, Navarro Maria Virtudes Saragossa, ES 1 9
Casanova, Rigat Isolda Saragossa, ES 7 9
Ferrer, Miralles Neus Barcelona, ES 5 29
Mangues, Bafalluy Ramón Barcelona, ES 6 9
Unzueta, Elorza Ugutz Barcelona, ES 8 9
Vázquez, Gómez Esther Barcelona, ES 7 9
Villaverde, Corrales Antonio Pedro Barcelona, ES 9 13

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