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United States of America Patent

PATENT NO 9587245
APP PUB NO 20140154707A1
SERIAL NO

13812605

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Abstract

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Transformed Phaeodactylum tricornutum including a nucleic acid sequence operatively linked to a promoter, wherein the nucleic acid sequence encodes an N-acetylglucosaminyltransferase I and/or an α-Mannosidase II and wherein at least one β-N-acetylglucosaminidase of the transformed Phaeodactylum tricornutum has been inactivated. A method for producing a glycosylated polypeptide includes the steps of (i) culturing a transformed P. tricornutum as defined previously and (ii) purifying the polypeptide that is expressed and glycosylated in the transformed P. Tricornutum. The use of such a transformed P. tricornutum for producing a glycosylated polypeptide is also described.

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Patent Owner(s)

Patent OwnerAddress
UNIVERSITE DE ROUEN1 RUE THOMAS BECKET MONT SAINT AIGNAN CEDEX 76821
L'INSTITUT FRANCAIS DE RECHERCHE POUR L'EXPLOITATION DE LA MER (IFREMER)155 RUE JEAN-JACQUES ROUSSEAU ISSY-LES-MOULINEAUX F-92138
ALGENICSPOLE BIO OUEST RUE DU MOULIN ROUSSELIERE SAINT HERBLAIN F-44800

International Classification(s)

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Baiet, Bérangère Rouen, FR 1 1
Bardor, Muriel Isneauville, FR 6 8
Burel, Carole Bourdainville, FR 3 8
Cadoret, Jean-Paul Basse Goulaine, FR 8 13
Carlier, Aude Nantes, FR 5 7
Lerouge, Patrice Grand Couronne, FR 8 52
Louvet, Romain Evreux, FR 1 2
Michel, Rémy Nantes, FR 2 1
Saint-Jean, Bruno Nantes, FR 1 2

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