Anti-ceramide monoclonal antibody 2A2

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United States of America Patent

PATENT NO 9592238
SERIAL NO

13974405

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Abstract

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We have discovered that administering anti-ceramide antibody treats and prevents an array of diseases mediated by cytolytic T lymphocyte (CTLs)-induced killing and by damage to endothelial microvasculture, including radiation-induced GI syndrome, Graft vs. Host diseases, inflammatory diseases and autoimmune diseases. We have also discovered new anti-ceramide monoclonal antibodies, that have therapeutic use preferably in humanized form to treat or prevent these diseases.

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Patent Owner(s)

Patent OwnerAddress
SLOAN KETTERING INSTITUTE FOR CANCER RESEARCH1275 YORK AVENUE NEW YORK NY 10021

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Arap, Wadih Houston, US 60 561
Kolesnick, Richard N New York, US 21 68
Pasqualini, Renata Houston, US 84 1135
Rotolo, Jimmy Andrew New York, US 13 23

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