Protein enriched microvesicles and methods of making and using the same
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United States of America Patent
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Mar 14, 2017
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app pub date -
May 15, 2014
filing date -
Jun 11, 2013
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Abstract
Protein enriched micro-vesicles and methods of making and using the same are provided. Aspects of the methods include maintaining a cell having a membrane-associated protein comprising a first dimerization domain and a target protein having a second dimerization domain under conditions sufficient to produce a micro-vesicle from the cell, wherein the micro-vesicle includes the target protein. Also provided are cells, reagents and kits that find use in making the micro-vesicles, as well as methods of using the micro-vesicles, e.g., in research and therapeutic applications.
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