Modified cytosine polynucleotide oligomers and methods

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United States of America Patent

PATENT NO 9598456
APP PUB NO 20150275283A1
SERIAL NO

14673494

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Disclosed are modified cytosine bases that provide enhanced base-pairing affinity for guanine bases in polynucleotide hybridization complexes. Also disclosed are polynucleotide oligomers, polynucleotide hybridization complexes that comprise such modified cytosine bases. Also disclosed are various methods of use. For example, in some embodiments, modified polynucleotide oligomers disclosed herein can be used as primers and probes for nucleic acid amplification and/or detection.

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Gall, Alexander A Woodinville, US 38 1065
Lokhov, Sergey G Bothell, US 25 294
Lund, Kevin Patrick Lynnwood, US 5 43
Podyminogin, Mikhail A Lake Forest Park, US 5 70
Viazovkina, Ekaterina V Lynnwood, US 4 1

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