Quantification of misfolded TNFR2:Fc

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United States of America Patent

PATENT NO 9598718
APP PUB NO 20160017403A1
SERIAL NO

14455183

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Abstract

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The present invention is directed to methods for determining the relative amount of wrongly disulphide bridged TNFR2:Fc in a sample of TNFR2:Fc, a fusion protein which is used in a variety of therapeutic applications. In addition, the invention pertains to a method for purifying TNFR2:Fc using said method for determining the percentage of wrongly disulphide bridged TNFR2:Fc, and to TNFR2:Fc compositions obtained thereby.

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Patent Owner(s)

Patent OwnerAddress
SANDOZ GMBHBIOCHEMIESTRASSE 10 KUNDL TIROL A-6250

International Classification(s)

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Fuchs, Michael Kundl, AT 72 431
Holzmann, Johann Kundl, AT 4 5
Lamanna, William Kundl, AT 2 4
Mayer, Robert Kundl, AT 58 1251
Posch, Christoph Kundl, AT 23 276
Rupprechter, Alfred Kundl, AT 2 4
Toll, Hansjorg Kundl, AT 2 4

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