Pharmaceutical compositions comprising active drugs, contraceptive kits comprising active drugs, and methods of administering the same
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United States of America Patent
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Mar 28, 2017
Grant Date -
Oct 15, 2015
app pub date -
Jun 23, 2015
filing date -
Jul 28, 2010
priority date (Note) -
In Force
status (Latency Note)
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Abstract
A pharmaceutical composition comprising an active contraceptive drug and one or more pharmaceutically-acceptable excipients. The pharmaceutical composition, when subjected to an in vitro dissolution test according to the USP XXIII Paddle Method, results in no more than 50% of said active drug initially present being dissolved within 30 minutes, and at least 50% of the active drug being dissolved in a time range from about 3 hours to about 4 hours. The pharmaceutical composition is administered daily to a patient having a BMI of about 25 kg/m2 or more for at least a portion of a treatment cycle. The pharmaceutical composition does not cause a number of days of bleeding events in the patient exceeding an average of 15% per treatment cycle in consecutive treatment cycles of administration after an initial treatment cycle of administration.
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Family
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