Compositions comprising TL1A-Ig fusion protein for the regulation of T regulatory cells, and methods for their use

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United States of America Patent

PATENT NO 9603925
APP PUB NO 20140286897A1
SERIAL NO

14185295

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Abstract

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Compositions comprising TL1A-Ig fusion proteins and methods of their use, e.g., for the treatment of diseases and disorders associated with antigen-specific immune responses, are described. Also described are combination therapies that include the administration of a TNFRSF25 agonist and an interleukin (e.g., IL-2) and/or an mTOR inhibitor (e.g., rapamycin).

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Patent Owner(s)

  • UNIVERSITY OF MIAMI

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Khan, Samia Q Miami, US 3 26
Podack, Eckhard R Coconut Grove, US 30 308
Schreiber, Taylor H Miami, US 11 33

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