Method for producing soluble recombinant interferon protein without denaturing

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United States of America Patent

PATENT NO 9611499
APP PUB NO 20160032345A1
SERIAL NO

14884081

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The present invention relates to the field of recombinant protein production in bacterial hosts. It further relates to extraction of soluble, active recombinant protein from an insoluble fraction without the use of denaturation and without the need for a refolding step. In particular, the present invention relates to a production process for obtaining high levels a soluble recombinant Type 1 interferon protein from a bacterial host.

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Patent Owner(s)

Patent OwnerAddress
PFENEX INC5501 OBERLIN DRIVE SAN DIEGO CA 92121

International Classification(s)

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Allen, Jeffrey Poway, US 142 2761
Chew, Lawrence San Diego, US 6 41
Feng, Ping-Hua San Diego, US 2 3
Haney, Keith L San Diego, US 3 3
Patkar, Anant San Diego, US 2 3
Sengchanthalangsy, Lei Lei Phokham Carlsbad, US 2 3

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