Mutant sodium channel Nav1.7 and methods related thereto

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United States of America Patent

PATENT NO 9617316
APP PUB NO 20140165219A1
SERIAL NO

13967306

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Abstract

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Described are mutant Nav1.7 sodium channel alpha-subunits and nucleic acid sequences encoding such mutants. Further described are methods for characterizing a nucleic acid sequence that encodes a Nav1.7 sodium channel alpha-subunit, methods for determining a Nav1.7 haplotype, methods for determining a subject's predisposition to a neurologic disorder associated with a sodium channel mutation, and methods of identifying a compound that modulates mutant Nav1.7 sodium channels. Other materials, compositions, articles, devices, and methods relating to mutant Nav1.7 sodium channels are also described herein.

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Patent Owner(s)

  • UNIVERSITY OF UTAH

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Leppert, Mark F Salt Lake City, US 18 93
Singh, Nanda A Heber City, US 6 35

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