Coordination complexes, pharmaceutical solutions comprising coordination complexes, and methods of treating patients
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United States of America Patent
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Apr 18, 2017
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app pub date -
May 29, 2014
filing date -
Oct 25, 2004
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Abstract
A coordination complex having a physiologically acceptable pKa includes a metal and a biologically active agent. The pKa of the coordination complex is less than the pKa of the biologically active agent. A pharmaceutical solution for treating a patient includes a coordination complex and water, wherein the coordination complex is at least partially soluble in the water at physiological pH and in a therapeutically efficacious concentration. A method for treating a patient includes administering a pharmaceutical solution including a coordination complex and water to a patient in need of a biologically active agent.
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