Engineering the production of a conformational variant of occidiofungin that has enhanced inhibitory activity against fungal species

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United States of America Patent

PATENT NO 9624270
APP PUB NO 20140147416A1
SERIAL NO

14090679

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Abstract

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Occidiofungin is a cyclic nonribosomally synthesized antifungal peptide with submicromolar activity. This invention is directed to compositions enriched for particular occidiofungin diastereomers/conformers, methods of making compositions enriched for particular diastereomers/conformers and microorganisms suitable for producing enriched compositions of particular diastereomers/conformers. Methods of treating fungal infections or plants infected by fungi are also provided.

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Patent OwnerAddress
THE TEXAS A&M UNIVERSITY SYSTEM3369 TAMU COLLEGE STATION TX 77843

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Gu, Ganyu Painter, US 6 14
Lu, Shien College Station, US 7 15
Ravichandran, Akshaya College Station, US 5 2
Smith, James Leif College Station, US 7 6

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