Fluorescent silica-based nanoparticles

Number of patents in Portfolio can not be more than 2000

United States of America Patent

PATENT NO 9625456
APP PUB NO 20130039848A1
SERIAL NO

13381209

Stats

ATTORNEY / AGENT: (SPONSORED)

Importance

Loading Importance Indicators... loading....

Abstract

See full text

The present invention provides a fluorescent silica-based nanoparticle that allows for precise detection, characterization, monitoring and treatment of a disease such as cancer The nanoparticle has a fluorescent compound positioned within the nanoparticle, and has greater brightness and fluorescent quantum yield than the free fluorescent compound To facilitate efficient urinary excretion of the nanoparticle, it may be coated with an organic polymer, such as polyethylene glycol) (PEG) The small size of the nanoparticle, the silica base and the organic polymer coating minimizes the toxicity of the nanoparticle when administered in vivo The nanoparticle may further be conjugated to a ligand capable of binding to a cellular component associated with the specific cell type, such as a tumor marker A therapeutic agent may be attached to the nanoparticle Radionuclides/radiometals or paramagnetic ions may be conjugated to the nanoparticle to permit the nanoparticle to be detectable by various imaging techniques.

Loading the Abstract Image... loading....

First Claim

See full text

Family

Loading Family data... loading....

Patent Owner(s)

Patent OwnerAddress
CORNELL UNIVERSITYCENTER FOR TECHNOLOGY LICENSING 395 PINE TREE ROAD SUITE 310 ITHACA NY 14850

International Classification(s)

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Bradbury, Michelle New York, US 3 154
Burns, Andrew Niskayuna, US 24 217
Larson, Steven New York, US 14 147
Lewis, Jason New York, US 76 920
Ow, Hoosweng Arlington, US 1 101
Penate, Medina Oula New York, US 4 104
Wiesner, Ulrich Ithaca, US 52 4695

Cited Art Landscape

Load Citation

Patent Citation Ranking

Forward Cite Landscape

Load Citation

Maintenance Fees

Fee Large entity fee small entity fee micro entity fee due date
11.5 Year Payment $7400.00 $3700.00 $1850.00 Oct 18, 2028
Fee Large entity fee small entity fee micro entity fee
Surcharge - 11.5 year - Late payment within 6 months $160.00 $80.00 $40.00
Surcharge after expiration - Late payment is unavoidable $700.00 $350.00 $175.00
Surcharge after expiration - Late payment is unintentional $1,640.00 $820.00 $410.00