Real time electronic cell sensing systems and applications for cell-based assays

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United States of America Patent

PATENT NO 9625472
SERIAL NO

13244004

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Abstract

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The present invention includes devices, systems, and methods for assaying cells using cell-substrate impedance monitoring. In one aspect, the invention provides cell-substrate impedance monitoring devices that comprise electrode arrays on a nonconducting substrate, in which each of the arrays has an approximately uniform electrode resistance across the entire array. In another aspect, the invention provides cellular assays that use impedance monitoring to detect changes in cell behavior or state. In some preferred aspects, the assays are designed to investigate the affects of compounds on cells, such as cytotoxicity assays.

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Patent Owner(s)

Patent OwnerAddress
AGILENT TECHNOLOGIES INC5301 STEVENS CREEK BLVD MS 1A-PB SANTA CLARA CA 95051-7201

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Abassi, Yama San Diego, US 10 393
Gan, Jiangbo San Diego, US 9 237
Wang, Xiaobo San Diego, US 339 5652
Xu, Xiao San Diego, US 131 2804

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