System and method for magnetic resonance imaging of intracranial vessel walls

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United States of America Patent

PATENT NO 9625548
APP PUB NO 20130335083A1
SERIAL NO

13922111

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Abstract

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A magnetic resonance imaging (MRI) system for intracranial vessel wall imaging. The MRI system includes a radio frequency (RF) coil system to irradiate radio frequency (RF) pulses into a region of interest and detect a plurality of RF response signals, and a signal processing unit adapted to analyze the plurality of RF response signals. The RF coil system arranges the RF pulses in a pulse sequence including an excitation pulse and refocusing pulses which induce corresponding flip angles. A minimum flip angle is in the range of 30 degrees to 65 degrees, and a maximum flip angle is in the range of 100 degrees to 150 degrees. The signal processing unit analyzes the RF response signals with a three-dimensional isotropic resolution of 500 cubic microns or less and orders the RF response signals in k-space to enhance contrast between intracranial vessel wall tissue and cerebrospinal fluid or blood.

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Patent Owner(s)

  • THE JOHNS HOPKINS UNIVERSITY

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Qiao, Ye Baltimore, US 1 9
Wasserman, Bruce A Baltimore, US 1 9

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