flagellin derivative in preparation of drug for preventing and treating inflammatory bowel diseases

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United States of America Patent

PATENT NO 9630999
APP PUB NO 20160060305A1
SERIAL NO

14940648

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Abstract

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The application of flagellin derivative CZLC31 from Salmonella in preparation of medicines for preventing and treating inflammatory bowel disease (IBD) is introduced in this invention. The CZLC331 protein has a good preventive and therapeutic effect for IBD, such as ulcerative colitis (UC) and Crohn's disease (CD) in this invention. Therefore, this protein can be prepared into the drug for prevention and treatment of IBD. It has been found that the bad efficacy, slow onset, long course of treatment, side effects can be significantly avoided for existing clinical IBD drugs, it can reduce the patient's pain during the treatment in this invention. The rehabilitation and quality of life of the patients have been largely improved. The drug will play an important role in the prevention and treatment of IBD in this invention, and has broad application prospects.

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Patent Owner(s)

Patent OwnerAddress
SUZHOU SCISCAPE BIOMEDICINE SCIENCE & TECHNOLOGY CO LTDJIANGSU 215021

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Gao, Yan Beijing, CN 159 1163
Li, Junhuai Jiangsu Province, CN 2 3
Li, Weiguang Beijing, CN 13 59
Li, Zhihui Beijing, CN 18 54
Wu, Yonghong Beijing, CN 10 34
Xu, Yang Beijing, CN 501 4586
Zhang, Chenggang Beijing, CN 14 4
Zhang, Yanchun Beijing, CN 3 4

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