Fluorogenic and chromogenic substrate

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United States of America Patent

PATENT NO 9632034
SERIAL NO

15068373

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Abstract

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The present invention provides near-infrared fluorogenic and/or chromogenic formulations, methods, systems and kits. Upon contacting an azine with an oxidant and a peroxidase, the azine is converted to an azine derivative which is both visibly colored and fluorescent. This invention also provides high sensitive methods to detect biological molecules, showing better sensitivity than chemiluminescence methods. Advantageously, the formulation and reaction is free of luminol or luminol derivatives.

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Patent Owner(s)

Patent OwnerAddress
LI-COR INC4647 SUPERIOR STREET LINCOLN NE 68504

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Padhye, Nisha Lincoln, US 11 31
Wang, Ying Lincoln, US 968 7243
Xu, Xinshe Lincoln, US 16 161

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