Cationic oil-in-water emulsions

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United States of America Patent

PATENT NO 9636410
SERIAL NO

14130886

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Abstract

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This invention generally relates to cationic oil-in-water emulsions that contain high concentrations of cationic lipids and have a defined oil:lipid ratio. The cationic lipid can interact with the negatively charged molecule thereby anchoring the molecule to the emulsion particles. The cationic emulsions described herein are useful for delivering negatively charged molecules, such as nucleic acid molecules to cells, and for formulating nucleic acid-based vaccines.

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Patent Owner(s)

  • SMITHKLINE BEECHAM BIOLOGICALS S.A.

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Brito, Luis Concord, US 30 615
Chan, Michelle Florence, US 19 237
Geall, Andrew Littleton, US 92 3340
O'Hagan, Derek Winchester, US 138 2357
Singh, Manmohan Cary, US 101 2141

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