Extracellular matrix films and methods of making and using same

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United States of America Patent

PATENT NO 9644177
SERIAL NO

13940739

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Abstract

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In one aspect, films that can serve as a model or mimic for the basal lamina are described herein. In some embodiments, a film described herein comprises a top surface and a bottom surface in facing opposition to the top surface, wherein the film is formed from Type I collagen and one or more additional extracellular matrix proteins. The additional extracellular matrix proteins, in some cases, comprise one or more of Type IV collagen, laminin, and fibronectin. Moreover, in some instances, the weight ratio of Type I collagen to the additional extracellular matrix proteins in the film is at least about 40:1.

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Patent Owner(s)

  • BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Banda, Sreevidhya Arlington, US 1 4
Kim, Young-Tae Arlington, US 90 1329
Tamuly, Deepika Arlington, US 1 4

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