Computer system and microfluidic instrumentation for next-generation biological signaling network research and applications
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United States of America Patent
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May 9, 2017
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Jun 9, 2011
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Jun 9, 2010
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Abstract
A computer-controlled micro-instrumentation biochemical reaction environment system includes an electrically-controllable microfludic routing system, at least one microreaction chamber, at least one micro-instrumentation device, and at least one electronic microprocessor. The microreaction chamber supports at least one chemical reaction associated with a biological signaling pathway. The micro-instrumentation device measures at least one physical quantity associated with the signaling pathway. The microprocessor transmits electrical control signals, receives electrical measurement signals, and executes at least one software algorithm. The microreaction chamber is connected to the microfludic routing system to receive and transmit at least a fluid or gas, and the electronic microprocessor receives electrical measurement signals from the micro-instrumentation device via a first electric interface and transmits electrical control signals to electrically-controllable microfludic routing system via a second electrical interface.
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