Recombinant mumps virus vaccine

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United States of America Patent

PATENT NO 9649371
SERIAL NO

14001228

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Abstract

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The present invention provides the complete genomic sequence of the epidemic mumps virus (MuV) strain MuVIowa/us/06. Further, a reverse genetics system was constructed and used to rescue recombinant viral constructs that are attenuated compared to MuVIowa/us/06 and JL vaccine viruses. Such constructs include viral constructs lacking the open reading frame (ORF) of the SH gene (rMuVΔSH) and/or incapable of expressing the V protein (rMuVΔV).

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Patent Owner(s)

  • UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC.

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
He, Biao Bogart, US 59 220

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