Water-soluble taxane derivatives and uses thereof

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United States of America Patent

PATENT NO 9650390
APP PUB NO 20170057973A1
SERIAL NO

15119603

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Abstract

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The present invention discloses a class of water soluble taxane derivatives, a method for treating tumor using the same, use thereof as anti-tumor drugs and use thereof in the preparation of anti-tumor drugs. The water soluble taxane derivatives have the general formula (I-1), (I-2) or (I-3): wherein, R1 is H or methyl; R2 is H, methyl or acetyl; R3 is phenyl or OC(CH3)3; X is H, C1-6 alkyl or F; Y is F or C1-6 alkyl substituted with one or more F; n is 1, 2, 3, 4, 5 or 6; W is NR4R5.A or

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Patent Owner(s)

Patent OwnerAddress
JIANGSU NHWALUOKANG PHARMCEUTICAL RESEARCH AND DEVELOPMENT CO LTDXUZHOU CITY JIANGSU 221000

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Chen, Dahai Chongqing, CN 3 110
Chen, Gang Chongqing, CN 944 8640
Li, Qingeng Chongqing, CN 8 6
Mao, Wei Chongqing, CN 101 482
Wang, Tao Chongqing, CN 1447 9693
Wang, Yuanzhong Chongqing, CN 17 12
Wu, Tong Chongqing, CN 171 1394
Zeng, Lingguo Chongqing, CN 8 7

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