Phosphoramidate derivatives of 5-fluoro-2′-deoxyuridine for use in the treatment of cancer

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United States of America Patent

PATENT NO 9655915
APP PUB NO 20160166596A1
SERIAL NO

14943555

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Abstract

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Phosphoramidate derivatives of 5-fluoro-2′-deoxyuridine are disclosed for use in the treatment of cancer, especially in the treatment of cancer where the patient shows resistance, for example, in a patient with cells with a lowered level of nucleoside transporter proteins and/or with nucleoside kinase-deficient cells and/or with mycoplasma-infected cells and/or with cells with a raised level of thymidylate synthase.

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Patent Owner(s)

Patent OwnerAddress
NUCANA PLCEDINBURGH EH12 9DT

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Balzarini, Jan Heverlee, BE 43 488
Gonczy, Blanka Cardiff, GB 7 82
McGuigan, Christopher Cardiff, GB 46 1233
Murziani, Paola Cardiff, GB 7 82
Slusarczyk, Magdalena Cardiff, GB 14 100

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