Long-acting coagulation factors and methods of producing same

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United States of America Patent

PATENT NO 9663778
SERIAL NO

14274061

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Abstract

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Polypeptides comprising at least one carboxy-terminal peptide (CTP) of chorionic gonadotropin attached to the carboxy terminus but not to the amino terminus of a coagulation factor and polynucleotides encoding the same are disclosed. Pharmaceutical compositions comprising the polypeptides and polynucleotides of the invention and methods of using and producing same are also disclosed.

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Patent Owner(s)

  • OPKO BIOLOGICS LTD.;OPKO BIOLOGIES LTD.

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Fima, Udi Eyal Beer-Sheva, IL 50 1341
Hart, Gili Shoham, IL 16 328

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